Lecture Notes - Moleculehalflife (A)decreasedor(B)increased

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Molecule half life These graphs show the rates of change in the intracellular concentrations of different  molecules when their rates of synthesis are either (A) decreased or (B) increased  suddenly by a factor of 10 Blue indicates half-lives for each molecule Red lines indicate molecules that are rapidly degraded Green lines indicate molecules that are slowly degraded Molecules that are more slowly degraded (A) are also more slowly produced (B) Proteins with key regulatory roles are often synthesized and degraded at very high rates  so that their concentration can be quickly regulated by the cell
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Most extracellular signals are hydrophilic molecules that bind cell  surface receptors Some signal molecules are hydrophobic enough or small enough to  traverse the plasma membrane and act inside the cell directly Nitric Oxide (NO), which is produced by endothelial cells subjected to 
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This note was uploaded on 02/22/2010 for the course BE 2400 taught by Professor Goldman during the Fall '08 term at Michigan Technological University.

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Lecture Notes - Moleculehalflife (A)decreasedor(B)increased

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