nov 6 signal trans handout

nov 6 signal trans handout - BIOLOGY315H Signal...

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BIOLOGY 315H Signal transduction November 6, 2006 Receptor proteins allow a cell to detect and recognize signals from its environment, but this recognition phase is only the first step in the cell's ability to respond to such signals. There are many ways in which a cell can respond to the presence of specific ligand - e.g. orienting towards (or away) from the source of the ligand; altering its pattern of gene expression; or producing electrical or chemical signals of its own. The sequence of molecular events by which the activation of any receptor leads to a cellular response is known as 'signal transduction'. Learning goals 1. A signal transduction pathway is a sequence of biochemical events that occur downstream of ligand binding, and that each of these events involves the activity of one or more signaling proteins. What does it mean to activate a signal transduction pathway? Can an activated pathway be inactivated, and if so why might this be important for the cell? 2.
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nov 6 signal trans handout - BIOLOGY315H Signal...

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