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Unformatted text preview: Transposons 11/22/06 Major ideas and questions: 1. Transposons are movable genetic elements. 2. Transposition can result in loss or gain of genes. 3. Transposons may alter expression of adjacent host genes. 4. What are the general mechanisms of transposition? 5. What are the common features of transposons and transposition? 6. How can transposition alter the genome and influence evolution? Something to think about: 1. There has been an outbreak of dysentery caused by Shigella dysenteriae . This strain of S. dysenteriae is resistant to amplicillin, ciprofloxacin, and trimethoprim, antibiotics typically used to treat the disease. This pattern of antibiotic resistance had not previously been seen in this strain. One of the patients from whom the Shigella was isolated also carried a harmless strain of E. coli that had the same antibiotic resistances. E. coli and Shigella are closely related and can exchange DNA by transduction, conjugation, and transformation. How could you determine whether this strain was able to transformation....
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- Fall '06