NS 115 - Lecture 10 - Lecture 10 September 22, 2008...

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Lecture 10 September 22, 2008 Hypoglycemia Normal Blood Glucose Levels o Alpha cells – detect a drop in glucose, and produces something called glucagons . Pancreas produces glucagons. Glucagon (hormone) acts on the liver and converts glycogen to glucose which gets released into the blood stream. o Problem – as glucose starts to go up again that stimulates insulin again and the glucose level will go down again. Otherwise you fluctuate between hypo- and hyperglycemia To fix this the delta cells produce a hormone called somatostatin Released about the same time the alpha cells release glucagons. It represses the insulin receptors and glucagons receptors in order to dampen the response. o Hypothalamus Major regulatory of autonomic function (sympathetic functions) Constantly monitoring blood glucose levels, in addition to alpha and beta cells. Senses that when blood glucose is low it will activate the sympathetic NS. In particular it activates the adrenal gland Outside part is called the adrenal cortex, the inside part the adrenal medulla.
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NS 115 - Lecture 10 - Lecture 10 September 22, 2008...

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