NS 115 - Lecture 32 - Lecture 32 Sodium November 19, 2008...

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Lecture 32 – Sodium November 19, 2008 Calcium – Blood Pressure Connection o Low consumption of calcium correlates with high blood pressure Low blood calcium causes greater excitability of smooth muscle (arteries o Calcium Supplements reduces blood pressure in people with low blood calcium Relationship is stronger than with dietary sodium Decrease in Blood Pressure o Kidneys Have cells that respond to the pressure of the blood that’s flowing through it Renin is released when blood pressure goes down It activates ACE Has an action on a peptide called angiotensin I (inactive) o Has active form and inactive from o Angiotension – converting Enzyme converts it to the active form It causes the arteries to contract Aldosterone Raises sodium in Kideys which spill out into the bloodstream raising blood pressure o Drugs ACE inhibitors Angiotensin II receptor blockers Block reapsorption of Na+ (diuretics) Sodium – Blood Pressure Connection
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NS 115 - Lecture 32 - Lecture 32 Sodium November 19, 2008...

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