Biol223_Smith_24_2007-2008Spring_ExamI -...

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Biol223_Smith_2007-2008Spring_ExamI 26 March 2008 PAGE 1 of 7 Biology 223 Spring 2007-2008 Exam I, 26 March 2008 EXAM COPY # No notes, no calculators, no phones, etc. Write your name and student ID number at the top of this page and most importantly, on the answer page . Only the answer page will be graded, you must place your answers in the space provided. Write legibly, if I cannot read or understand your answer, you will receive no credit. If it takes too much effort, you may lose points. It may help if you show your work below the question in the body of the exam. Unanswered questions receive no credit. Within parts of multi-part questions, incorrect answers will subtract from correct parts. Unjustifiable, frivolous, and grossly incorrect answers may be assigned negative points. Thus, it is possible to receive a negative score on the exam. If you find any mistakes of mine in the question, note it on your exam and you may receive extra credit. 100 points possible Russell, 2nd edition, chapters 1, 2, 3, 4, 11, 12, 15, 16 Note points per question and spend your effort accordingly!
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Biol223_Smith_2007-2008Spring_ExamI 26 March 2008 PAGE 2 of 7 Question 1 for 10 points If a million nucleotide RNA were synthesized of random sequence and composition (A:C:G:U=1:1:1:1), and N means any base, Y means either pyrimidine, and R means either purine, a) how many times would you expect the specific sequence 5'-GNYRA-3' to occur? b) how many times would you expect the same sequence to occur if the RNA were synthesized without C? a) b) Question 2 for 8 points In a prototrophic strain of Neurospora crassa , intermediate A is made from components of minimal medium by enzyme 1, et cetera. Consider the following hypothesis diagrammed below, where compounds D, E, and H are essential, but intermediate B is toxic . Consider possible mutant strains (1-8), each lacking only the eponymous gene, and determine which strains would grow in minimal medium supplemented with a single compound (A-H). In other words, if the strain is null in gene X, in which media would it grow? There may be
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Biol223_Smith_24_2007-2008Spring_ExamI -...

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