Cancer study Final!!!!!!!!!!!!!!!!!!

Cancer study Final!!!!!!!!!!!!!!!!!! - Breast Cancer Name :...

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Breast Cancer Name : Tamoxifen in Treating Women With Breast Cancer Phase : Phase III Description : Estrogen can stimulate the growth of breast cancer cells. Hormone therapy using tamoxifen may fight breast cancer by blocking the uptake of estrogen by the tumor cells. The objective of this study is to compare the disease-free and overall survival of women with early breast cancer who are randomized to discontinue adjuvant tamoxifen against those randomized to continue for at least 5 additional years. Patients discontinue tamoxifen after at least 2 years of prior treatment. Add more to this section?!?!?!? Background : Tamoxifen (Nolvadex®) is a drug, taken orally as a tablet, which interferes with the activity of estrogen, a female hormone. (Medterms.com) Estrogen can promote the development of cancer in the breast. Tamoxifen is approved by the U.S. Food and Drug Administration (FDA) for the prevention of breast cancer and for the treatment of breast cancer, as well as other types of cancer. As adjuvant therapy (treatment given after the primary treatment to increase the chances of a cure), tamoxifen helps prevent the original breast cancer from returning and also helps prevent the development of new cancers in the other breast. (Clinicaltrials.gov) As treatment for metastatic breast cancer, this drug slows or stops the growth of cancer cells that are present in the body. Some breast cancers are classified as estrogen receptor-positive (also known as hormone sensitive), which means that they have a protein to which estrogen will bind. These breast cancer cells need estrogen to grow. Tamoxifen works against the effects of estrogen on these cells. (Cancer.gov)
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Cancer study Final!!!!!!!!!!!!!!!!!! - Breast Cancer Name :...

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