10.17.09 ~ 9.20 ~ Draelos ~ Treatment of Xerosis

10.17.09 ~ 9.20 ~ Draelos ~ Treatment of Xerosis -...

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Treatment of Xerosis: Distinguishing One Emollient from Another Zoe Diana Draelos, MD High Point, North Carolina Consultant Research Funds NuSkin L’Orea L Oreal Signum Biosciences Beiersdorf Colgate-Palmolive Neutrogena What characterizes adequately moisturized skin? What characterizes poorly moisturized skin? Moisturization and the Skin Barrier Brick and Mortar Model of the Stratum Corneum Lipid Corneocyte (protein) Ordered Epidermal lipids Covalently bound lipid layer on corneocyte surface
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What is the skin barrier? Protein rich corneocytes Intercellular lipids Surface lipid Surface lipids Water proof interlocking mortar and brick model Separates the environment from the body How can the skin be moisturized? Not by spraying water on the skin Not by drinking 8 glasses of water per day Not by laying wet towels on the skin Not by covering it with plastic wrap Not by sitting in a high humidity warm sauna How can the skin be moisturized? Skin moisturization increases with improved barrier function Skin moisturization increases with Skin moisturization increases with improved barrier function Skin moisturization increases with improved barrier function What is the normal water content of the skin? Approximately 30% Too much water creates maceration and decreased physical resistance to trauma Too little water creates cracks and fissures through which water is lost to a lower humidity environment
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10.17.09 ~ 9.20 ~ Draelos ~ Treatment of Xerosis -...

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