October 10 - {aim #20} @cfofim, 10, 2008 @ Ken-Lego...

Info iconThis preview shows pages 1–3. Sign up to view the full content.

View Full Document Right Arrow Icon
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 2
Background image of page 3
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: {aim #20} @cfofim, 10, 2008 @ Ken-Lego mmcfim Wl‘Lj'fi/ Teen/beam. 2° substrates can form both 8N2 and E2 products. The stronger and bulkier the base (nucieophile), the more E2 product. 52 5 2; C' (59 OCH CH / . A + CH3CH2 ——> + 2 3 cam 36:35am it, b e. A . , . /L/q , as; m 7 / / 25/ W17:— cults nams‘fé ME... 75% °o . . . o - J ' c A of. mam: 2 Mk ’6 wéSojoaoqubLofefl/tht (McygL/Dr‘w-dbL “(5) f e M d,— Mete. CI 0 OK A + ———-I- A /U\Oe A L9H 2 AeoLMa/Lajé—g Aegov‘tpi)‘ Make/z, 100% BAD/144$ We, ,' Wat-Lem we ew%/@MLCWC1‘?L ‘ a) Br JD" 69 5C 076%»? X + CEgCHZ /J\ 100% 0 tum 3 (MW [6 6 :7 gnaw/1361:; bevee. . . \ 1f, “£0 (flflaod mud: albwfe, (wwou’tim hflda—Wm EA atom General gundelmes so far. GWL W Ge, W ODE/2% Mae. ) 20 (WA/1% 440 SM}, Nucleo 3 U S'i'EcL baa/ea, Nuc/Fec—lo/Kdge. 1:6 an, Wadi/gm)“. 6 2 + cfiqua 34 M 6L. N I Q E 2, fade-atmd: fidaWWOd—éfi 6N2, {Ma-us Wb‘f’fi, E 2/ PA I 5L— Phedme’af JE/zeoLWmaflE; (jazz, (SN 2 nemot'mm) « Adam. Ametvaa Jimeng /&~azm «is mew > 1‘"; 2°>>>3 o flf confi/WW (IA/t CM dm/L’g‘rvp/ a kS‘li'eM/Lc, efim We ‘60-, Eta-W ,ofljlunjés aim mam dutgmfixag, CM’g‘m/l’ emu oLemuvse, 6N2 A513: 9 Ltd/{IELWOLQJLQQL To M%£%W'CLL + (BMW, meleofam ..._._~;, ASLLbS-tb‘fwm 'fLQ-‘o'bmct mw‘fi) SE0” awe, MOLWOL fuzz &i& + Warm/3mg, a 6N“ 52 3M u‘ th nhnfi. llxmfinln fiszrlanhR.‘i/s '-... Bf? m-,P. {Dunner-.4- all/10"?“ .i LI. f,Na\ 0m]? M oé/ooie xg-cuses <96 amok deem/bfiéfie daze/6.0V \ /—\ figmet'c 'Afleen‘ Nucleophiies and nucleophilicity f 4% N “H. What is nucleophificity and how do we measure it? 1“— '—_—"'—'—— CH O (SN 2 /1_e @6wa . . ‘ _ CH I +N'uL——=p ‘BM"°"'+ V“ Frequently encountered nucleophlles 3 “130+: aj‘ng/Lo m ' I flu? Very good Good Farr Weak Veryweak . :9 Br% 9 Fe 0:9 H20, ROH RCOZH flange M R38 HO RO NH3 Rooéa (3 j fiesta, H 0N9 N9 £M%)“tt7fwe, 14% creoP’gbd/bé No‘tLe. : muclwfflgfw Me. me [ea/3’34"?“ flat/moot; cL abw 9,44,) . _ J . office“. we vume Wa mue—vt/ Mono—am 1 When comparing two nucleophiles, how do you tetl which is better? If the nucleophilic atom is the same: If the nucleophilic atoms are in the same period: if the nucleophilic atoms are in the same group: -Noummo a 23%282 av -35 n 3:38sz Q -ommo n sagas; fie mommo u 23%232 3 QmEQ ozaaofloaz + hm\/\ $36.3.“ £5 E 3.2 Beams.“ 2: 3 8mm: 3:95 23.32%: 53>? wcam “a hochQO E é mzm “mm Ev fizm “S Q Mm g azm “E Q m m g 1m 4m 9; fizm Q: OWEQ cameos is: + Q/ \j/ £4553“ mmoo momma 5 35¢ a :35 m S m o m M : PUMP“ me 5233.” £5 E “ESSA? macs—Huth E mew-«553.3 Emmfimaoefi £355 2% you mhmfifimm owm_:m:omg m5 “363% $3 3 .335 3% g h$35 ...
View Full Document

This note was uploaded on 02/25/2010 for the course CHEM 3311 at Colorado.

Page1 / 3

October 10 - {aim #20} @cfofim, 10, 2008 @ Ken-Lego...

This preview shows document pages 1 - 3. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online