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Class 9 - Linkage and mapping What did Mendel say when...

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Linkage and mapping What did Mendel say when asked, “why did the chicken cross the road?” To get a road map To see if it was dominant
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In the test cross above what is the arrangement of the alleles? A. B. C. 2 Wild-type female Aa Bb Curly wings, orange eyes aabb X : A b a B a b a b a b A B a b a b A B a b a b a b D . A or B E. A,B, or C X X X
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In the test cross above what is the arrangement of the alleles? A. B. C. 2 Wild-type female Aa Bb Curly wings, orange eyes aabb X : A b a B a b a b a b A B a b a b A B a b a b a b D . A or B E. A,B, or C X X X
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3 alleles in cis alleles in trans
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3 alleles in cis alleles in trans
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3 alleles in cis alleles in trans
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17 What is the recombination frequency between curly and orange? A. 0.16 B. 0.31 C. 0.49 D. 0.50 E. 0.69 150 Wild-type Wild-type female Aa Bb Curly wings, orange eyes aabb 1,000 total progeny a = mutant version of curly A = normal version of curly b = mutant version of orange B = normal version of orange Normal dominant over mutant for both 160 curly wings, orange eyes 340 normal wings, orange eyes 350 curly wings, normal eyes X Progeny:
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20 150 Wild-type 350 curly wings, normal eyes Wild-type female Cc Oo Curly wings, orange c c o o 1,000 total progeny X Progeny: A b a B a b a b a b A B a b a b a b A b a B a b Recombination Frequency (rf): # Recombinants/Total Progeny (150+160)/1000= 0.31 160 curly wings, organge eyes 340 normal wings, orange eyes What is the recombination frequency between curly and orange ? A. 0.16 B. 0.31 C. 0.49 D. 0.50 E. 0.69 a = mutant version of curly A = normal version of curly b = mutant version of orange B = normal version of orange Normal dominant over mutant for both
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6 It is important to realize that crossing over produces reciprocal products A B a b X A b a b a B a b produced in equal proportions
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Given the recombination rate predict the outcome of a cross Given RF = 16% between T and D, what is the expected frequency of gamete Td? a) 8% b) 16% c) 25% d) 50% 7
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Given the recombination rate predict the outcome of a cross Given RF = 16% between T and D, what is the expected frequency of gamete Td? a) 8% b) 16% c) 25% d) 50% 7 RF is the total recombination rate for both reciprocal products so one of the two products is 1/2 the total
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So, now what about frequency of offspring of a cross? 8 Given the same recombinant fraction (16%) how may Warty dull pickles would you expect to see if you examined 100 progeny? A) 84 B) 42 C) 16 D) 8
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So, now what about frequency of offspring of a cross? 8 Given the same recombinant fraction (16%) how may Warty dull pickles would you expect to see if you examined 100 progeny? A) 84 B) 42 C) 16 D) 8
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So, now what about frequency of offspring of a cross? 8 Given the same recombinant fraction (16%) how may Warty dull pickles would you expect to see if you examined 100 progeny? A) 84 B) 42 C) 16 D) 8
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So, now what about frequency of offspring of a cross?
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