Class 18 - The central dogma and how new diversity arises...

Info iconThis preview shows pages 1–15. Sign up to view the full content.

View Full Document Right Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: The central dogma and how new diversity arises What is the nature of “mutations”? What are the ‘natural processes’ that cause mutations?-Remember that DNA is deoxyribonucleic acid-a chemical and that it is sitting in mostly water-It is exposed to enzymes and environmental compounds that can change the fundamental nature of the DNA and/or its nucleotide components Causes of Mutations : Depurination, about 1000 times/hr in human Tautomeric shifts of pyrimidines Effects of different point mutations 8 Please answer this question without talking to your neighbor 9 One type of dwarfism results from the production of mutant SHR-1 protein. You look at the length of the mutant SHR-1 and the normal (wild-type) SHR-1 protein, and discover that the mutant SHR-1 protein has fewer amino acids. What do you expect to find when you examine the DNA sequence? A. nucleotides were deleted B. additional nucleotides were added C. one nucleotide was changed D. without additional information, any of the above are possible 10 Now turn to your neighbor and talk about the question 11 One type of dwarfism results from the production of mutant SHR-1 protein. You look at the length of the mutant SHR-1 and the normal (wild-type) SHR-1 protein, and discover that the mutant SHR-1 protein has fewer amino acids. What do you expect to find when you examine the DNA sequence? A. nucleotides were deleted B. additional nucleotides were added C. one nucleotide was changed D. without additional information, any of the above are possible 12 Here is the answer, I will tell you how to solve it in a minute 13 14 A type of human dwarfism results from the production of mutant SHR-1 protein. You look at the length of the mutant SHR-1 and the normal (wild-type) SHR-1 protein, and discover that the mutant SHR-1 protein has fewer amino acids....
View Full Document

This note was uploaded on 02/25/2010 for the course MCDB 2150 taught by Professor Winey,mark during the Spring '06 term at Colorado.

Page1 / 29

Class 18 - The central dogma and how new diversity arises...

This preview shows document pages 1 - 15. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online