Class 19 - Molecular Review Review of molecular genetics...

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Unformatted text preview: Molecular Review Review of molecular genetics 1.DNA Replication 2.Transcription 3.Translation 4.Mutation/mutagenesis DNA Replication Executive summary DNA is double-stranded anti-parallel helix The strands are not identical - they are complementary DNA replication is semiconservative Strand identical with mRNA = C ODING Strand transcribed from = T EMPLATE 3 DNA POLYMERASE can ONLY create new DNA in a 5’ to 3’ direction Replication is SEMI-CONSERVATIVE the original strands remain Every round of DNA replication produces two new double stranded molecules - on strand is old, one is newly synthesized from nucleotides Transcription Starts at promoter in DNA RNA Polymerase synthesizes RNA 5’ to 3’ direction ONLY mRNA is identical to coding strand of DNA mRNA is inverse complement of template strand Transcription ends at terminator mRNA contains elements inside to later direct translation 6 Transcription starts when factors recognize doubles stranded...
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This note was uploaded on 02/25/2010 for the course MCDB 2150 taught by Professor Winey,mark during the Spring '06 term at Colorado.

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Class 19 - Molecular Review Review of molecular genetics...

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