Cytoskeleton structure - T h e C y t o s k e le t o n 1 1...

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1 The Cytoskeleton 11/28/07 •cytoplasmic networks of protein filaments and fibers •extends from nucleus to the plasma membrane. •responsible for cell shape, movement within cells, movement of entire cell, some cell-cell connections •contains three types of elements: Microfilaments (actin) Microtubules (tubulin) Intermediate filaments •movement powered by ATP hydrolysis, through: (a) polymerization and de-polymerization (b) interactions with motor proteins •actin and tubulin gene families have evolved •good examples of tissue-specific gene expression The fibrous proteins that form the cytoskeleton are polymers , each fiber being formed by the addition of thousands of identical protein subunits. The three components of cytoskeleton differ by type of molecule and by structure: 3 types by structure: Microfilaments, Intermediate filaments, Microtubules. Three types of filaments by function: A. Intermediate (various proteins) - hold cell shape, support nuclear membrane, help connect cells (desmosomes) B. Microtubules (tubulin) - move and organize the organelles C. Microfilaments (actin) - underlie plasma membrane,
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This note was uploaded on 02/27/2010 for the course BIO 45632 taught by Professor Saxena during the Spring '08 term at University of Texas at Austin.

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Cytoskeleton structure - T h e C y t o s k e le t o n 1 1...

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