H183 Lecture 9 - Uganda claims 250,000 people 1901 Joseph...

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Prevalence of Chagas Disease in Brazil From Coutinho and Pinto, “The Rise and Fall of Chagas Disease,” Perspectives on Science 7.4 (1999) South Africa Map: http://www.warmuseum.ca/cwm/exhibitions/boer/boerwarmap-lrg_e.shtml
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H183 Lecture: Trypanosomiasis Geography : Natal, South Africa; Zulu Kingdom Nyasaland (Malawi) Gambia Uganda Lassance, Brazil Terms: Parasites Sleeping Sickness Trypanosome (type of protozoa) African Trypanosomiasis Tsetse fly Trypanosoma brucei gambiense Trypanosoma brucei rhodesiense Atoxyl (an acid made from arsenic) Surra Suramin/Germamin (South) American Trypanosomiasis Chagas Disease Triatomine (Kissing Bug) – Triatoma infestans Trypanosoma cruzi People : Joseph Dutton (1874-1905) David Bruce Carlos Chagas (1879-1934) Dates : 1894 David Bruce studies nagana – a Zulu word for a cattle disease 1896-1906 Sleeping sickness epidemic in
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Unformatted text preview: Uganda claims 250,000 people 1901 Joseph Dutton identifies trypanosomes as cause of human sleeping sickness 1903 British Sleeping Sickness commission identifies tsetse flies as transmitter of human sleeping sickness 1905 Anton Breinl and John L. Todd begin use of Atoxyl to treat sleeping sickness (later shown to cause blindness) 1907 Alphonse Lavaren wins Nobel Prize in Physiology for research on protozoa 1909 Carlos Chagas discovers a new disease in Lassance, Brazil 1933 Carlos Chagas dies 1935 Renewed efforts to combat Chags Disease in Brazil and Argentina 1960s Resurgence of sleeping sickness in several African countries World Distribution of Malaria and Trypanosomiasis (Sleeping Sickness and Chagas Disease) Michel Tibayrenc, Finn Kjellberg, and Francisco J. Ayala, "The Clonal Theory of Parasitic Protozoa," BioScience, 1991 41: 767-74....
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H183 Lecture 9 - Uganda claims 250,000 people 1901 Joseph...

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