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Drugs_and_ETOH_Lecture

Drugs_and_ETOH_Lecture - Alcohol and Other Drugs The...

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1 Alcohol and Other Drugs Alcohol and Other Drugs The Biology and Consequences of Drug and Alcohol Use and Abuse GM Roybal, M.D., M.P.H. October 17, 2006 HP 200, Fall 2006 Overview: Overview: Biology of Drugs and Alcohol Biology of Addiction – Difference between Tolerance, Addiction, Dependence Social, Economic and Medical Impact of Drug and Alcohol Use and Abuse Fortified Wine
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2 The Reward Pathway and The Reward Pathway and Addiction Your Brain at Work.
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3 Natural Rewards Natural Rewards Food Water Sex Nurturing Exercise VTA = Ventral Tegmental Area Dopamine
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4 Addiction: A state in which an organism engages in a compulsive behavior even when faced with negative consequences. – Bad Grades – Losing Job – DUI – Divorce – Jail The Action of Morphine The Action of Morphine Binding Sites of Opiates
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5 Tolerance: Tolerance: A state in which an organism no longer responds to a drug – A higher dose of the drug is required to achieve the same effect Reward Pathway and Opiates The Action of Cocaine The Action of Cocaine
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6 Binding Sites of Cocaine Caudate Nucleus Reward Pathway and Cocaine Use
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