Lecture 4 posted - Test for#1 Test for#2 Phenotype Sample 1...

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BIO 311D LECTURE 4 Microevolution (population genetics) and the process of natural selection
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Hardy-Weinberg p p 2 + 2pq + q + 2pq + q 2 = 1 = 1
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Hardy-Weinberg Find: Frequencies of the alleles A and a. The genotypic frequencies of AA, Aa and aa.
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The Hardy-Weinberg equation p (f) p q (f) q p 2 homozygous dominant individuals q 2 homozygous recessive individuals 2pq heterozygous individuals
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Conditions which must be met for a population to be in Hardy-Weinberg equilibrium Random mating No mutations No gene flow (population is isolated) Very large population size (no genetic drift) No natural selection
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So what’s the point of it? (The Hardy-Weinberg theorem)
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Genetic variation changes in a population Gene flow Genetic drift Natural selection
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Genetic Drift ® candies: Phenotype Sample 1 Sample 2 Sample 3 Sample 4 Sample 5 Blue 5 1 7 0 13 Non-blue 48 52 47 53 40 Frequency (blue) 9% 2% 13% 0% 25%
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Why are there differences in the frequency of Hypothesis one: Hypothesis two:
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Unformatted text preview: Test for #1: Test for #2 Phenotype Sample 1 Sample 2 Sample 3 Sample 4 Sample 5 Blue 45 51 57 43 54 Non-blue 452 448 445 459 450 Frequency (blue) 10% 10% 11% 9% 11% 1. Call/email factory ( http://global.mms.com/us/ ) Frequency of blue = 10% 2. Bigger sample size: The Pounder FYI: M&M color make-up Brown 13% 30% Yellow 14% 20% Red 13% 20% Orange 20% 10% Blue 24% 10% Green 16% 10% Genetic drift: special cases Founder effect Bottleneck effect Examples of bottlenecks Founder effect Natural Selection Fitness Modes of natural selection: Stabilizing selection Directional selection Disruptive selection Balanced polymorphisms Heterozygote advantage 10-20% 5-10% 1-5% Sickle Cell Disease Genotypes Relative fitness Hb-N Hb-N 0.85 Hb-N Hb-S 1.0 Hb-S Hb-S 0.0 Frequency-dependent selection Sexual selection Sexual dimorphism Intrasexual selection Intersexual selection Natural selection is a cause of adaptive evolution...
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This note was uploaded on 02/28/2010 for the course BIO 49405 taught by Professor Chinnery during the Spring '10 term at University of Texas.

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Lecture 4 posted - Test for#1 Test for#2 Phenotype Sample 1...

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