19-COGS11-mind-body-and-disease

19-COGS11-mind-body-and-disease - Stress Disorders The...

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Stress Disorders Mind-Body The Interaction in Disease Mary ET Boyle, Ph.D. Department of Cognitive Science Minds and Brains
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Mind and physical illness. .. • Mind plays an important role in physical illness •Early days of medicine: ancient Greeks • Mind affects course of illness Minds and Brains
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After antibiotics. .. • New assumption • Infection, inflammatory disease limination of foreign organism or agent • Elimination of foreign organism or agent that causes illness nored the fact that the body can • Ignored the fact that the body can influence susceptibility to disease Minds and Brains
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Relationship between immune system. .. • Network that allows the brain and immune system to signal to each other. • Continuous and rapid • Immune system chemicals signal the rain brain • Brain sends chemicals back to immune ystem to restrain it system to restrain it. Minds and Brains
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Disruption of this communication system. .. • Disruption by: herited xacerbates the diseases that Inherited –Drugs oxic substances Exacerbates the diseases that these systems guard against: – Toxic substances – Surgery nflammatory autoimmune and Inflammatory, autoimmune, and associated mood disorders Minds and Brains
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Three components of an emotional response: behavioral autonomic hormonal •Prepare • Muscular • Facilitate the behaviors ympathetic • Reinforce •Adrenal edulla • Attack posture of a dog Sy pat et c Nervous System activated medulla • Epinephrine & norepinephrine Minds and Brains Can have an adverse effect on health.
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How is homeostasis maintained? • Brain responds – threatening situations with stress • Immune system responds – Pathogens and foreign molecules A substantial proportion f human cellular of human cellular machinery is dedicated to maintaining it Minds and Brains
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4 Levels of Homeostatic Regulation 1 •Internal reflexes; organs regulate their own function 2 •Autonomic nervous system and endocrine system rainstem and hypothalamus 3 •Brainstem and hypothalamus igher brain centers 4 •Higher brain centers ; integrate emotional activity , memory, awareness to modulate output from the brainstem & hypothalamus Minds and Brains
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Hypothalamus ituitary land N. tractus solitarius Locus ceruleus Pituitary gland Lymph node Brain stem hymus drenal gland Thymus Spleen idney Adrenal gland Vagus nerve Minds and Brains Bone Marrow Liver Kidney
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The stress response. .. • Physiological changes Must be regulated or else. .. – Focused attention –Fear Disorders emerge: rousal – Flight or fight hibitory behaviors arousal thought & feeling Inhibitory behaviors – Feeding ex Sex – sleep Minds and Brains
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The immune system response. .. • Bar pathogens from body •Recognize and destroy those that do gy • Neutralize dangerous toxins acilitate repair of damages/worn • Facilitate repair of damages/worn tissues • Dispose of abnormal cells Its response is so POWERFUL it needs constant regulation!!
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This note was uploaded on 03/02/2010 for the course COGSCI 11 taught by Professor Maryb. during the Spring '10 term at UCSD.

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19-COGS11-mind-body-and-disease - Stress Disorders The...

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