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Unformatted text preview: responsible locus II. Transposition A. DNA transposons B. Retroviruses & retrotransposons III. Overview of gene expression IV. Bacterial gene expression A. Transcription and transcription signals 1. RNA polymerase holoenzyme = core ( 2 , , ) + . 2. Polymerase recognizes genes by presence of specific promoter sequences. 3. Operator regions (specific DNA sequences) regulate expression of many genes. 4. Transcription terminates at specific sites where stem-loop structures form in RNA. B. Translation in prokaryotes 1. Requires ribosome, tRNA, aminoacyl-tRNA synthase and other factors. 2. Specific ribosome binding site proximal to AUG start codon. 3. Co-translational, polycistronic mRNA common....
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- Winter '10