9.Glycogen metabolism 2010

9.Glycogen metabolism 2010 -...

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Structure of glycogen Voet/Voet Fig. 18-1
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Questions to Ponder The mechanism of phosphoglucomutase is analogous to the mechanism of the mutase in the glycolytic pathway. Based on this information 1. Indicate what cofactor you think participates in this reaction. 1. Propose a series of steps by which this reaction is probably occurring.
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The debranching enzyme Voet/Voet Fig. 18-5
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Voet/Voet Fig. 18-56 UDP–glucose pyrophosphorylase
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The branching of glycogen Voet/Voet Fig. 18-8
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Glycogenin in the core of the glycogen particle http://upload.wikimedia.org/wikipedia/co
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Unformatted text preview: mmons/6/6d/Glycogen_structure.png About 30,000 Glc units are found in most glycogen particles. Problem to work on Synthesize the following disaccharide starting from glucose using reactions analogous to those in glycogen synthesis. Note – most sugar epimerization reactions occur on UDP-derivatives of the sugars. Indicate what cofactors/coenzymes would be required at each step. Remember that most reactions occur with nucleotide derivatives or phosphorylated derivatives of sugars. O O OH OH HOH 2 C O HOH 2 C...
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This note was uploaded on 03/03/2010 for the course CHEM 431 taught by Professor Pielak during the Spring '07 term at UNC.

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9.Glycogen metabolism 2010 -...

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