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103Lect2powerptpdf

103Lect2powerptpdf - GLUCOSE GLUCOSE written by Jeff Barry...

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Glucose -- ah, sugar sugar -- You are my favorite fuel From the blood-borne substrate pool. Glucose -- monosaccharide sugar -- You're sweeter than a woman's kiss 'Cause I need you for glycolysis. I just can't believe the way my muscles take you in. (For you, they'll open the door.) All it takes is a little bit of insulin (To upregulate GLUT4). Ah, glucose -- ah, sugar sugar -- You help me make ATP When my predators are chasing me. Ah, glucose -- you're an aldehyde sugar, And you're sweeter than a woman's kiss 'Cause I need you for glycolysis. I just can't believe the way my muscles break you down. (My glycogen is almost gone.) A few more seconds and I'll be rigor mortis-bound. (Acidosis done me wrong.) Your sweet is turning sour, baby. I'm losing all my power, baby. I'm gonna make your muscles ache. No, no, no! I'm swimming in lactate, baby. Yes, I'm swimming in lactate, baby. Now I'm drowning in lactate, baby. I'm gonna make your muscles ache. No, no, no! I'm drowning in lactate, baby. Ah, glucose -- ah, sugar sugar -- I used you up and you left me flat; Now I'll have to get my kicks from fat. Oh, glucose, glucose, sugar, sugar, The honeymoon is over now. GLUCOSE, GLUCOSE written by Jeff Barry and Andy Kim scientific lyrics by Greg Crowther http://www.science-groove.org/Now/Glucose.mp3
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1. Carbohydrates( CHOs=sugars=saccharides ) : Polyhydroxyaldehydes or Polyhydroxyketones or Substances which give these on hydrolysis. Most (not all) have the empirical formula of [CH 2 O] n . Number of Cs in smallest CHO? 3! C O H CX R 1 C O CX CX R 1 R 2 OH HB pg 3
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2. Fischer projection : We use two ways to visualize three dimensional CHOs on a two dimensional piece of paper. One is the Fischer projection. Horizontal lines represent bonds projecting out of the plane of the paper toward us, and vertical lines represent bonds projecting behind the paper with OH groups arranged to the left or right. H HO Fischer projection H HO By convention- Carbon-carbon bonds are vertical. HB pg 3
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Fischer projection http://upload.wikimedia.org/wikipedia/commons/e/e3/Fischer_Projection2.png
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H HC OH H HO OH H OH H CH 2 OH CH 2 OH O H HO OH H OH H CH 2 OH O D-Fructose= F D-Glucose=GLC an aldose a ketose 3.
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