103Lect6powerpt

103Lect6powerpt - C O H 3 C ScoA CH 2 COO- CH 2 COO- HO...

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Unformatted text preview: C O H 3 C ScoA CH 2 COO- CH 2 COO- HO COO- CH 2 COO- C CHCOO- COO- CH 2 COO- HC H COO- COO- OH CH 2 COO- C H H COO- O NAD NADH CO 2 CH 2 COO- C H H ScoA O NAD NADH + CO 2 COO- CH 2 CH 2 COO- CoASH GDP + Pi GTP + CoASH FADH 2 FAD COO- C C-OOC H H H 2 O C COO- C H HO H H COO- NAD NADH + H + ISOCITRATE !-KETO- GLUTARATE SUCCINYL CoA C COO- H 2 C COO- O Acetyl CoA H 2 O H 2 O H 2 O TCA CYCLE CITRATE cis-aconitate enzyme-bound OXALOACETATE FUMARATE SUCCINATE MALATE 1 2 3 4 5 6 7 8 CoASH + H + 2 Systematic Common 1. citrate synthase citrate OAA-lyase (acetyl CoA forming) 2. aconitase citrate hydro-lyase 3. isocitrate dehydrogenase isocitrate:NAD+ oxidoreductase(decarboxylating) 4. !-ketoglutarate dehydrogenase complex !-ketoglutarate dehydrogenase system 5. succinyl CoA synthetase succinate:CoA ligase (GDP forming) 6. succinate dehydrogenase succinate:FAD oxidoreductase 7. fumarase malate hydro-lyase 8. malate dehydrogenase (MDH) malate:NAD+ oxidoreductase HB 33 C O- O CHOH C !...
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103Lect6powerpt - C O H 3 C ScoA CH 2 COO- CH 2 COO- HO...

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