103Lect7Sp08

103Lect7Sp08 - HPO42- H2O GLC GLC-6-P HPO42- H2O DHAP F-6-P...

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Gluconeogenesis GLC GLC-6-P F-6-P F-1,6-bisP H 2 O HPO 4 2- H 2 O HPO 4 2- ATP ADP DHAP G-3-P glycolysis glycolysis 3PGA 2PGA PEP PYRUVATE LACTATE 1,3bis PGA NADH NAD + H + ATP ADP in animals X X X HB 38
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Gluconeogenesis PYRUVATE LACTATE NADH NAD + H + in animals PYRUVATE ATP ADP HCO 3 - HPO 4 2- OAA PEP GTP CO 2 GDP Mitochondrion PC PEPCK PEP GLC GLC-6-P F-6-P F-1,6-bisP H 2 O HPO 4 2- H 2 O HPO 4 2- ATP ADP DHAP G-3-P glycolysis glycolysis 3PGA 2PGA 1,3bis PGA ATP ADP Some new enzymes are required to convert lactate to glucose HB 38
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OXALOACETATE GTP GDP + 14 CO 2 C OPO 3 2- CH 2 O - O PEP PEP Carboxykinase (PEPCK) C CH 2 14 COO- O C O - O localization varies among species: only mitochondrial only cytosolic both Gluconeogenetic Reaction HB 35
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Gluconeogenesis GLC GLC-6-P F-6-P F-1,6-bisP H 2 O HPO 4 2- H 2 O HPO 4 2- ATP ADP DHAP G-3-P glycolysis glycolysis 3PGA 2PGA PEP OAA MALATE PYRUVATE LACTATE ALANINE 1,3bis PGA PYRUVATE ATP ADP HCO 3 - HPO 4 2- OAA MALATE PEP GTP CO 2 GDP NADH NAD + H + NAD + H + NADH GTP CO 2 GDP NADH NAD + H +
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103Lect7Sp08 - HPO42- H2O GLC GLC-6-P HPO42- H2O DHAP F-6-P...

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