1 SANES CH. 1 2009 FINAL (2)

1 SANES CH. 1 2009 FINAL (2) - Development of the NS Sanes,...

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Development of the NS Sanes, Reh and Harris Chapter 1: Neural Induction Have you handed in your Big Issues summary #1 via the Digital Dropbox? + Have you handed in your synopsis of the General Interest paper for Chapter 1? Good job
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Important concepts from chapter 1: 1. Both vertebrate and invertebrate animals make excellent model systems for the study of neural development. 2. The nervous system is not present at birth: it must be induced by pluripotential precursor cells to develop from the ectoderm. The CNS of INVERTEBRATES develops on the ventral (belly) side of the body, in VERTEBRATES it develops on the dorsal (back) side. 3. Neurons and glia are induced when mesodermal cells release one or more molecules that block a reaction among ectodermal cells letting them default to neural cells. This was learned through clever experiments. An important message of this chapter is that cell-to-cell signaling in early development occurs through signal-receptor interactions.
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2009 discovery: plant gene that Induces resistance to heat stress!! Control of the mitotic cycle in plants by cyclins: shared with animals WikiAnswers.com: We share 50% of our genes with banana plants Conclusion: there is only one biological solution for reproduction in living things, plants or animals, on this earth. DNA is a mechanism created by the cell to store information, and DNA is made of the same 4 nucleotides in every living thing. Mendel’s Laws of Heredity were worked out in peas and published in 1865 In 1953 Crick walked into the Eagle pub. . .
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*C. elegans Ultra-simple invertebrate round worm *Fruit Fly: most common Invertebrate model COMMON VERTEBRATE MODEL SYSTEMS *Zebra fish Frog Chick *Mouse *Human NEURONS •= completely sequenced genome. Look up: genomenewsnetwork.org Very primitive, only 2 germ layers: neurons arise from the ectoderm Single celled animals = No neurons Where are Nervous systems found in the Animal kingdom? How many disease genes are shared? e.g., PKU
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2001 A “ P” element is a transposon that is present in the fruit fly Drosophila melanogaster and is used widely for mutagenesis and the creation of genetically modified flies used for genetic research. A P-element is used as a mutagen --------------Barbara McClintock---------------- Transposons are sequences of DNA that can move around to different Positions within the genome of a single cell, a process called transposition . In the process, they can cause mutations
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This note was uploaded on 03/06/2010 for the course NSC 269 taught by Professor Ebner during the Spring '10 term at Vanderbilt.

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1 SANES CH. 1 2009 FINAL (2) - Development of the NS Sanes,...

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