6 Sanes Ch 6.2 only 2009

6 Sanes Ch 6.2 only 2009 - Chapter 6 part 2 Sanes Reh and...

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Chapter 6 - part 2 Sanes, Reh and Harris Example maps in the brain and their construction
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The 'little person' exists, but is very distorted by receptor density. The dermatomes on the left are mapped onto the cortical surface as shown on the right. Sensory area 4 The homonculus Spinal nerve distributions a.k.a. dermatomes Sensory-Motor Cortex
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Large scale map changes in the somatic sensory cortex. Distal arm amputation causes changes in cortex, but proximal amputation causes changes in the DRG, thalamus and cortex.
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Raccoons have specialized their hand area cortex to where each digit has a separate gyrus to receive somatic sensory information and catch crayfish underwater.
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Rat's explore with their whiskers in the dark and barrel field cortex has one cell column in cortex for each whisker on the face V-I V-I A-I A-I OLF OLF Medial Medial Lateral Lateral Flattened, CO stained Left Hemisphere Flattened, CO stained Left Hemisphere through layer IV through layer IV Anterior Anterior SI Cortex A B C D E Posterior Posterior Somatic sensory pathways from whiskers to S-I (barrel) cortex with topographic coding in the trigeminal nuclei and thalamus before creating the map in S-I cortex
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There are many interactions between the periphery and the cortex . The normal pattern of barrels in mouse barrel cortex formed on PND 4 and named by row and arc. If mice are bred until one is found that has an extra whisker, there will be an extra barrel in cortex. If the B3 whisker follicle is destroyed just after birth, its cortical barrel will be taken over by surrounding inputs. If 2 whiskers are glued together after birth their cortical barrels fuse into a single domain. Cortical Barrels
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The retinotopic map in mammalian visual cortex is the result of two topographic transformations. From the location of ganglion cells in each hemi-retina to separate monocular zones in LGN to an expanded, fovea-dominated binocular hemi-map in primary visual cortex (a.k.a. V-I or striate cortex). V-I is located on the upper and lower banks of the calcarine fissure
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The all rod cat retina has no fovea, just a visual streak of higher ganglion cell density
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Bat echolocation is a type of biosonar that requires unique computational maps in auditory cortex
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This note was uploaded on 03/06/2010 for the course NSC 269 taught by Professor Ebner during the Spring '10 term at Vanderbilt.

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6 Sanes Ch 6.2 only 2009 - Chapter 6 part 2 Sanes Reh and...

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