Cell Biology Fall 2004 Exam 2

Cell Biology Fall 2004 Exam 2 - Principles of Cell Biology...

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Principles of Cell Biology Exam 2 Fall 2004 October 28, 2004 Directions: There are 75 questions in this exam with only one correct answer. 1. Secretory proteins are secreted by the cell through either constitutive or regulated secretion. Which of the following is characteristic of regulated, but not constitutive, secretion? a. Small, electron dense vesicles b. Affected immediately by the addition of protein synthesis inhibitors c. Regulated by exogenous ligands such as insulin d. Proteins are synthesized in the cytosol, not on the rough endoplasmic reticulum e. Characteristic of proteins such as those of the extracellular matrix 2. Which of the following in the Protein Kinase C system is a breakdown product of PIP2 (PI 4,5- bisphosphate)? a. Phosphatidylinositol (PI) b. PI 4-phosphate (PIP) c. 1,2 diacylglycerol (DAG) d. Inositol 1,4,5 trisphophosphate (IP3) e. Both c and d 3. cAMP is linked to what type of receptor system? a. Steroid receptors b. Cytokine receptors c. Ion-channel receptors d. Receptor tyrosine kinases e. G protein-coupled receptors 4. A nascent protein with a single stop-transfer anchor sequence will end up being a. A single-pass, Type I, integral membrane protein with the amino end exposed to the extracellular medium b. A single-pass, Type II, integral membrane protein with the carboxy end exposed to the extracellular medium c. A secretory protein d. A protein destined for the lysosome e. A serpentine protein like G-linked receptors. 5. The voltage-dependent influx of external calcium to the inside of the cell is critical to the function of what type of cell junction? a. Desmososme b. Hemi-desmosome c. Tight junction d. Gap junction e. Neurochemical junction 6. In the rod photoreceptor system what enzyme is dis-inhibited through the removal of two gamma subunits that once dis-inhibited, ultimately leads to phototransduction? a. cAMP dependent protein kinase b. cGMP dependent protein kinase c. cAMP phosphodiesterase d. cGMP phosphodiesterase e. not yet known
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7. Which of the following proteins is synthesized on the rough endoplasmic reticulum? a. Proteins destined to be secreted b. Proteins destined to translocate to the nucleus c. Proteins destined to translocate to the mitochondria d. Proteins destined to translocate to the chloroplast e. All of the above 8. 8-azido- 32 P-cAMP is what type of a label? a. Photoaffinity label b. radioactive c. analogue of cAMP d. all of the above e. none of the above 9. Which of the following systems describes the release of a hormone that travels primarily through the blood system? a. Endocrine b. Pheromonal c. Paracrine d. Autocrine e. synaptic 10. The nicotinic and muscarinic acetylcholine receptors are two different receptors both of which bind acetylcholine. Which of the following is correct about either of these channels? a.
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Cell Biology Fall 2004 Exam 2 - Principles of Cell Biology...

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