mcb110_alber_biological_membranes

mcb110_alber_biological_membranes - BiologicalMembranes1...

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    Biological Membranes 1 MCB 110 - Fall 2007 -  Alber MCB 110: Biological Membranes Tom Alber 321 Stanley Hall tom@ucxray.berkeley.edu /courses/mcb110 Office Hours:  2-3 PM, Thursdays and Fridays (with exceptions!!)  
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    Biological Membranes 2 MCB 110 - Fall 2007 -  Alber 1 MEMBRANE LIPIDS AND LIPID BILAYER I Intro to Biological Membranes II Membrane Lipids III Lipid Self-Assembly IV Membrane Fluidity 2 MEMBRANE PROTEINS I Introduction to Membrane Proteins II Integral Membrane Proteins III Peripheral Membrane Proteins IV Lipid-Anchored Membrane Proteins V Diffusion of Membrane Proteins 3 TRANSPORT ACROSS MEMBRANES I Intro: Permeability of the Cell Membranes II Diffusion III Facilitated Diffusion IV Active Transport V Membrane Potential and Nerve Impulses 4 MEMBRANE TRAFFICKING I Introduction: Secretory Pathway II Endoplasmic Reticulum   III Golgi IV Vesicle Transport V Lisosomes VI Endocytosis 1 CELL SIGNALING I Introduction II G Protein-coupled Receptors III Receptor Tyrosine Kinases IV Integrin Signaling V Cell Signaling and Apoptosis VI Relationships between MCB 110 BIOLOGICAL MEMBRANES
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    Biological Membranes 3 MCB 110 - Fall 2007 -  Alber Suggested Reading : Lodish, Chapter 5 - 5.1; Alberts,  Chapter 10 
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    Biological Membranes 4 MCB 110 - Fall 2007 -  Alber
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    Biological Membranes 5 MCB 110 - Fall 2007 -  Alber
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    Biological Membranes 6 MCB 110 - Fall 2007 -  Alber
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    Biological Membranes 7 MCB 110 - Fall 2007 -  Alber
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    Biological Membranes 8 MCB 110 - Fall 2007 -  Alber
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    Biological Membranes 9 MCB 110 - Fall 2007 -  Alber
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    Biological Membranes 10 MCB 110 - Fall 2007 -  Alber
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    Biological Membranes 11 MCB 110 - Fall 2007 -  Alber
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    Biological Membranes 12 MCB 110 - Fall 2007 -  Alber IV Membrane Fluidity IV A – Definition and Function Fluidity  is defined as “easy of flow” and is opposed to viscosity (resistance to flow). Lipids bilayer are fluid in the liquid crystal state, but under the  melting temperature Tm  become rigidified:  liquid crystal to gel  transition. Fluidity of a biological membrane is required for  movement of membrane proteins, and for processes  requiring membrane fusion such as cell division or  exocytosis IV B – Effect of Lipid Composition Very sensitive to the presence of  unsaturated  fatty chains  (one or more double bonds) that make packing difficult and thus  decrease the Tm. In contrast saturated lipids have very high  melting temperatures. The 
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This note was uploaded on 03/08/2010 for the course MCB 110 taught by Professor Alber,zhou,nogales during the Fall '07 term at University of California, Berkeley.

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mcb110_alber_biological_membranes - BiologicalMembranes1...

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