SummaryofQuestionsforFinalinPrevYears-2

SummaryofQuestionsforFinalinPrevYears-2 - Sample Questions...

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Sample Questions from Final Exam from Previous Years 1. The following cell survival data are for mammalian cells exposed to x-rays in the presence or absence of oxygen. They fit the multi-target model of cell kill. Dose(Gy) SF Dose(Gy) SF 15 0.42 4 0.5 27 0.11 8 0.18 39 0.017 12 0.027 54 0.0025 16 0.0042 63 0.00045 20 0.00067 a) Plot the data on the attached semi-log axes. b) On the graph, identify which curve represents data from oxygenated cells and which curve represents data from un oxygenated (hypoxic) cells. c) On the same graph, sketch the curve you would expect to see if the cells were irradiated at very low dose rate . Label this curve. d) On the same graph sketch the curve you would expect to see if the cells were irradiated with α -particles instead of x-rays. Label this curve. 2. Oxygen dissolved in tissue acts as a radiosensitizing agent. Describe the mechanism of this effect. 3. Choose one of the three acute radiation syndromes and describe (a) how death to the individual occurs and (b) why
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This note was uploaded on 03/09/2010 for the course 22 22.01 taught by Professor Smith during the Fall '09 term at MIT.

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SummaryofQuestionsforFinalinPrevYears-2 - Sample Questions...

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