CH369.lecture12 - Pasteur effect His discoveries reduced...

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Unformatted text preview: Pasteur effect His discoveries reduced mortality from puerperal fever , and he created the first vaccine for rabies . His experiments supported the germ theory of disease . He was best known to the general public for inventing a method to stop milk and wine from causing sickness, a process that came to be called Louie Pasteur Pasteur effect Pasteur effect Pasteur effect Rate of glucose consumption by yeast cells decreased dramatically when the cells were shifted from anaerobic to aerobic growth conditions. The Warburg effect (W) More aggressive cell line, MDA-MB- 231, has much higher glucose consumption in the presence of oxygen than the MCF-7 cells with a non-invasive phenotype. Basis for PET Under anaerobic condition- glycolysis.-2ATP + 4ATP _______ Net: 2ATP __________ 38 ATP Under aerobic condition CAC The Citric Acid Cycle Is Both Catabolic and Anabolic Six of the eight citric acid cycle intermediates (all except isocitrate and succinate) are precursors or products of other substances Citric acid cycle intermediates as biosynthetic precursors amino acids -ketoglutarate to glutamine Transamination reaction G ~ 0 Anaplerotic reactions of the citric acid cycle...
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CH369.lecture12 - Pasteur effect His discoveries reduced...

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