380 10 Lec 2

380 10 Lec 2 - Biology 380 Immunology Lec. 2: Innate...

Info iconThis preview shows pages 1–2. Sign up to view the full content.

View Full Document Right Arrow Icon
Biology 380 Spring 2010 Immunology Henson Lec. 2: Innate Immunity I 1. We’ll be covering cells and organs of the immune system starting in lab on Friday. Group exercise: Diagram an immune response to a virus. 2. Innate immunity = rapid, fixed, limited specificity and constant Adaptive immunity = slow, variable, highly selective and improves over time 3. Innate immune system barriers to infection A. Physical/anatomical/mechanical barriers. B. Physiological/chemical barriers. C. Cellular-mediated protection. D. Microbiological 4. The inflammatory response is fundamentally innate in nature. A. Macrophages and neutrophils are professional pathogen killers. - Have surface receptors that recognize pathogens. - Pathogens undergo phagocytosis and are killed by specific mechanisms. - Neutrophils (and Eosinophils) trap bacteria in DNA nets. - Exit the blood stream by the process of extravasation mediated by lectins. (Video = Inner Life of a Cell) B. Macrophages release cytokines that modulate the inflammatory response. - Important cytokines include TNF-
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 2
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 03/09/2010 for the course BIO 380 taught by Professor Henson during the Spring '10 term at Dickinson.

Page1 / 2

380 10 Lec 2 - Biology 380 Immunology Lec. 2: Innate...

This preview shows document pages 1 - 2. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online