Unformatted text preview: multiple myeloma. C. Rodney Porter, Gerald Edelman, and Alfred Nisonoff chemically dissect antibodies and discover Fab, Fc and light & heavy chains. 4) Antibody structure. A. Antibody arms are connected by a flexible hinge region B. Heavy and light chains contain variable and constant regions. C. The immunoglobulin fold domain. Note: Antibody structure and diversity generation is covered in Chap 4. Recall that you need to answer the questions (they will be posted later today) about the Fuch’s paper (currently available on Blackboard) prior to coming to class on Friday. Fuchs et al., 2007. Novel cell death program leads to neutrophil extracellular traps. J. Cell Biol. 176:231-241....
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- Spring '10
- Biology, multiple myeloma, mhc restriction, AGS, MHC II restriction