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Unformatted text preview: What are the differences seen in neutrophils undergoing apoptosis versus necrosis versus NET generation? How does the TUNEL method indicate that cells are undergoing apoptosis? 4) In Fig 5 explain how the DPI treatment blocked NET formation and how treatment with GO was able to induce NETs even in DPI-treated neutrophils. Why was catalase and its inhibitor AT included in some of these experiments and what were the results? What are PBMCs? 5) In Fig 6 why were CGD patient neutrophils included in this study and why were NET not produced by these cells with PMA treatment but were produced with GO treatment? Explain the method used to measure ROS production shown in Fig 5i....
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- Spring '10