Drugs_Classical_Conditioning

Drugs_Classical_Conditioning - Drugs & Learning The Role of...

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The Role of Classical Conditioning in Understanding Drug Effects Drugs & Learning
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Drug Tolerance Definition : A diminished response to a drug with use.
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Example of Tolerance Mean Latency to Lift Paw Pain No Pain Trials Analgesia Control Group (Inject Saline-->Formalin) Morphine Group (Inject Morphine --> Formalin) 1 2 3 4
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Tolerance (Expressed as a Dose-Response Curve) Mean Latency to Lift Paw Pain No Pain Doses of Morphine (log) Analgesia Low ------------> High First Time of Drug Use After Repeated Drug Use
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Sources of Drug Tolerance 1) Metabolic Tolerance 2) Physiological Tolerance 3) Behavioral Tolerance : Tolerance that is influenced by Pavlovian and instrumental learning processes.
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Shep Siegal’s (1977) Experiment Group Phase 1 Test 1) Paired Light Morphine Light Morphine and and Tone Tone 2) Unpaired Light /Morphine Light Morphine and and Tone Tone 3) CS Alone (Saline) Light Saline Light Morphine and and Tone Tone DV: Latency to lift paw from a warm surface at the time test.
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Results
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This note was uploaded on 03/10/2010 for the course PSYCH 110 taught by Professor Rauhut during the Spring '10 term at Dickinson.

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Drugs_Classical_Conditioning - Drugs & Learning The Role of...

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