Exam 1 2009 - Your Name_KEY MCMP 442 Exam I 8:00-10:00 PM Room WTHR 200 Instructions 1 2 3 There are 13 pages including the cover and scoring pages

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1 Your Name __________ KEY __________________________ MCMP 442 Exam I 8:00-10:00 PM Room WTHR 200 February 12, 2009 Instructions: 1. There are 13 pages including the cover and scoring pages, and 37 questions. Please make sure that you have all of the pages before you start working on the examination. 2. Please write your name on the cover page of the exam. 3. Read each question carefully before you start to answer it. If you have questions about the exam, ask! Regrading policy: 1. If you feel that a question has not been graded correctly, return the entire exam within one week to Professor Cushman. Attach a note about the error. Professor Cushman will regrade the entire examination. This means you could either gain or lose total points. 2. If there is an error in addition of points, return the exam with a note to that effect. The examination will be totaled correctly without regrading the entire exam.
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2 Scoring Page (50) 1-25 ______ (4) 26 ______ (12) 27 ______ (4) 28 ______ (4) 29 ______ (4) 30 ______ (3) 31 ______ (4) 32 ______ (4) 33 ______ (2) 34 ______ (2) 35 ______ (4) 36 ______ (3) 37 ______ Total ______
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3 For Questions 1 – 25, indicate the correct answer by filling in the appropriate choice on the Scan Tron sheet. Each question is worth 2 points. Also indicate your response on this exam by filling in the correct letter in the space provided or by circling the correct letter. ______________________________________________________________________________ For each of the following clinical tests, indicate which feature or property of a pathogen is being detected? Each letter can be used once, more than once, or not at all. One letter per blank. a. Nucleic acid b. Cell wall c. Antigen d. Antibodies e. Biochemical activity 1. ____ b ___ Gram Stain 2. ____ d ___ ELISA All answers accepted in the end! Antibodies in ELISA come from host 3. ____ a ___ Fluorescent in situ hybridization (FISH) 4. ____ c ___ Indirect immunofluorescence 5. ____ e ___ Blood agar plates 6. ____ a ___ Polymerase chain reaction (PCR) ______________________________________________________________________________ For questions 7 – 10, indicate which pharmacological parameter listed below best fits the description. Each letter can be used once, more than once, or not at all. One letter per blank. a. Cmax/MIC b. Time > MIC c. Time > MBC d. Cmax e. MBC/AUC 7. ___ d ____ Refers to the peak serum drug concentration 8. ___ a ____ Should be at least 16 for an antibiotic to be effective in an immunocompromised patient 9. ___ b ____ Parameter to be optimized for an antibiotic that displays time-dependent bactericidal activity 10. ___ a ____ Parameter to be optimized for an antibiotic that displays concentration-dependent bactericidal activity
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4 11. Which of the following pathogens are intracellular throughout the entire course of their life cycle? a.
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This note was uploaded on 03/11/2010 for the course MCMP 341 taught by Professor No during the Spring '10 term at Purdue University-West Lafayette.

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Exam 1 2009 - Your Name_KEY MCMP 442 Exam I 8:00-10:00 PM Room WTHR 200 Instructions 1 2 3 There are 13 pages including the cover and scoring pages

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