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exam 4 2008 - MCMP 442 MCMP 442 Exam III 7:00 PM EE 129...

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MCMP 442 Exam 4 2008 Last 5 digits of PUID _______________ 1 MCMP 442 Exam III 7:00 PM, EE 129 April 16, 2008 ANSWER KEY Name: _________________________________________ Last 5 digits of your student ID number: _______________ INSTRUCTIONS 1. There are 12 pages including the cover and scoring pages, and 35 questions. Please make sure that you have all of the pages before you start working on the examination. 2. Please write the last 5 digits of your student ID number on the cover page of the exam, and on the bottom of each subsequent page . 3. Read each question carefully before you start to answer it and provide the information requested. When discussion is called for, do not exceed the space available . If you have questions about the exam, ask! EXAMINATION REGRADE POLICY Do not take the time to read this now! Read it when you get back the graded exam. 1. If you feel that a question has been graded incorrectly, return the entire exam within one week to Professor LaCount. Attach a note about the error. Professor LaCount will regrade the entire examination. 2. If there is an error in addition of points, return the exam with a note to that effect. The lost points will be cheerfully refunded; no regrade is necessary
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MCMP 442 Exam 4 2008 Last 5 digits of PUID _______________ 2 Scoring Page Question (point value) Score 1-15 (30) _____ 16 - 30 (45) _____ 31 (6) _____ 32 (6) _____ 33 (4) _____ 34 (6) _____ 35 (3) _____ Total (100) _____
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MCMP 442 Exam 4 2008 Last 5 digits of PUID _______________ 3 Matching (Each question is worth 2 points) Write the letter of single best answer for each question in the blank beside the number AND darken the corresponding circle on the Scantron sheet. Each letter may be used once, more than once, or not at all. ______________________________________________________________________________ Group 1 a. amphotericin B b. fluconazole c. flucytosine d. miconazole e. posaconazole 1. ___ d __ can only be used topically 2. ___ b __ azole that penetrates the CNS 3. ___ e __ broadest spectrum azole antifungal 4. ___ c __ converted to its active form by a fungal enzyme 5. ___ a __ lipid formulations reduce toxicity ______________________________________________________________________________ Group 2: 6. ___ e __ nonpeptidomimetic HIV protease inhibitor 7. ___ a __ analogue of deoxyguanosine that can cause hypersensitivity reactions 8. ___ c __ chelates metal ions and inhibits DNA strand transfer 9. ___ d __ contains a phosphonate functional group 10. ___ b __ recommended protease inhibitor for initial antiretroviral therapies ______________________________________________________________________________
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MCMP 442 Exam 4 2008 Last 5 digits of PUID _______________ 4 Group 3: For each of the following pairs of drugs, what effect will resistance to the first drug likely have on the second drug? a. cross-resistance b. hypersensitivity c. no effect 11. ___ c __ caspofungin and amphotericin B 12. ___ b __ lamivudine and tenofovir 13. ___ c __ fluconazole and flucytosine 14. ___ c __ enfuvirtide and maraviroc 15. ___ a __ amantidine and rimantidine ______________________________________________________________________________
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MCMP 442 Exam 4 2008 Last 5 digits of PUID _______________ 5 Multiple choice. Circle the single best answer for each question AND darken the corresponding circle on the Scantron sheet. Each question is worth 3 points.
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