quiz 2 2007

quiz 2 2007 - 1. Moduretic is a combination diuretic...

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1. Moduretic is a combination diuretic containing Hydrochlorothiazide (HydroDiuril) and Amiloride (Midamor). A. What is the therapeutic advantage of this combination? (3 points) The amiloride will reduce potassium loss caused by HCTZ…the combo will reduce K+ loss. B. What effect will Moduretic have on calcium excretion? Explain (3 points) It will decrease calcium excretion (1 pt) The HCTZ (1 pt) will cause the Na/Ca exchanger(transporter/antiporter) to increase activity due to decreased intracellular Na+ levels, thus promoting Ca++ movement back into the body (increased reabsorption). 2. For each of the following anti-hypertensive agents indicate whether the drug alters blood pressure by primarily affecting peripheral vascular resistance (PVR), cardiac output (CO), or both PVR and CO. (2 points each) NOTE: THESE ARE IN A DIFFERENT ORDER ON THE GREEN QUIZZES A. Bisoprolol (Zebeta) Both CO and PVR B. Clonidine (Catapres) Both CO and PVR C. Prazosin (Minipres) PVR
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quiz 2 2007 - 1. Moduretic is a combination diuretic...

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