quiz%203 - 1. Describe three effects of angiotension II...

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1. Describe three effects of angiotension II that lead to a slow pressor response. (2 pts each) a. Increase Na+ reabsorption in proximal tubule b. synthesis and release of aldosterone from adrenal cortex c. alter renal hemodynamics (could also say) -renal vasoconstriction -enhanced NE effects in kidney 2. a. What effect would ibuprofen (Motrin) have on the effectiveness of enalopril (Vasotec)? (3 pts) Reduce effectiveness (1 pt). Part of enalopril effects are mediated through bradykinin (1 pt), which requires prostaglandins to cause vasodilation-ibuprofen would block PG’s and the vasodilation (1 pt) b. How would Motrin impact the effectiveness of candesartan (Atacand)? Explain. (3 pts) No effect (1 pt)…candesartan is a Ang II antagonist (ARB) (1 pt) which is not dependent on bradykinin or prostaglandins for effectiveness (1 pt).
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3. With regards to lisinopril (Zestril, Prinivil) and fosinopril (Monopril): a. Describe two differences between these drugs. (2 pts each) i. Any two of the following:
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This note was uploaded on 03/11/2010 for the course MCMP 123 taught by Professor -- during the Spring '10 term at Purdue.

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quiz%203 - 1. Describe three effects of angiotension II...

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