Wi10-Lec6 - Lecture 6 Enzymes Cell Division and Cancer What...

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1 Lecture 6 Enzymes, Cell Division and Cancer What is Lactose Intolerance?
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2 What would happen if the enzymes in your body never stopped? Inhibitors • Block the enzyme binding site • Prevent substrate from binding Æ stops reaction • Cells use inhibitors all the time – to slow down reactions that are going too fast, or when the products of the reaction are not needed enzyme inhibitor Substrate cannot bind
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3 Enzyme Inhibitors as treatment for disease • Antiretroviral drugs—inhibit HIV proteases • Viagra—inhibits a phosphodiesterase – Allows smooth muscle cells to relax Æ increases blood flow all over the body Cell Division and Cancer
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4 “Cancer cells are those which have forgotten how to die.” —Harold Pinter Or How to stop dividing… Learning Objectives 1. Know that cell division (mitosis) is accomplished by the creation of an exact duplicate of the “mother cell” 2. Know the number of chromosomes in each cell in the human body, and how they are replicated before cell division 3. Understand the basic phases of the cell cycle and what parts of the cell are involved 4. Know what makes a cancer cell different from a noncancerous dividing cell
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Wi10-Lec6 - Lecture 6 Enzymes Cell Division and Cancer What...

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