BIPN 102 Lecture Notes

BIPN 102 Lecture Notes - nda: rection to Daltons Law nge...

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Henry’s Law lation Fick’s law of diffusion d space Ventilation/perfusion ratio quation Diffusion Limited gas exchange Perfusion Limited gas exchange enda: rrection to Dalton’s Law veolar Gas Exchange nry’s Law k’s law of diffusion rfusion Limited gas exchange ffusion Limited gas exchange ntilation/perfusion ratio ect of gravity on ventilation and perfusion ange diffusion of gasses from alveoli to blood limited v. perfusion limited gas exchange on V / Perfusion Q matching y blood flow gravity on V / Q differences of ventilation and blood flow B I P N 1 0 2 L e c t u r e N o t e s | 1 Chapter 17 Respiratory System Lecture 1 9/26/09 VII. Agenda: i. Respiration ii. Anatomy and histology iii. Gas laws Poiseuille’s Law Boyle’s Law Dalton’s Law Henry’s Law La Place VIII. Overview of Respiration i. Exchange 1: outside world to lungs ii. Exchange 2: alveoli in lungs to blood (diffusion of gasses)
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B I P N 1 0 2 L e c t u r e N o t e s | 2 iii. E xchange 3: diffusion of oxygen gas from capillary to the cell, and of carbon dioxide gas from the cell to the capillary IX.Exchange 1: external respiration or ventilation (how air moves in and out of lungs) i. Also involves matching the rate of exchange with the outside world to the rate of exchange between the lungs and blood X. Exchange II: i. Gasses are somewhat insoluble at higher temperatures Carbon dioxide is twenty times more soluble than oxygen : Therefore, oxygen transport includes hemoglobin : Carbon dioxide acts as a buffer that maintains pH in the extracellular compartments a. CO 2 + H 2 0 H 2 CO 3 : By altering respiration, you can change pH XI.Exchange III:
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B I P N 1 0 2 L e c t u r e N o t e s | 3 i. Cellular respiration in the mitochondria create a concentration gradient of carbon dioxide and oxygen, which allows for diffusion of gasses ii. Oxygen goes into the mitchochodria and carbon dioxide comes out iii. There is as higher concentration of carbon dioxide in the cell than in the blood, causing the carbon dioxide to leave the cell iv. There is a higher concentration of oxygen inside the blood than in the cell, so the oxygen will leave the blood XII. Anatomy Summary i. The upper respiratory tracts include the larynx and pharynx ii. The lower respiratory tract includes the trachea, bronchioles, bronchi, lungs iii. The diaphragm separates the abdomen and the thorax. When the diaphragm relaxes, air is pushed out of lungs (expiration) iv. When diaphragm contracts, it expands the lungs and air goes in (inspiration) XIII. The two lungs i. The left lung is smaller than the right lung The heart is closer to the left lung than to the right ii. The left lung has two lobes Superior Inferior iii. The right lung has three lobes Superior Middle Inferior iv. The pericardium is the fluid that surrounds the heart in the pericardial cavity v. The pleuracardium is the fluid that surrounds the lungs in the pleural cavity vi. The amount of fluid is very small but it is very important Allows for lubrication
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BIPN 102 Lecture Notes - nda: rection to Daltons Law nge...

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