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Unformatted text preview: 3/12/10 1 The experiments of Mangold and Spemann in 1924, on transplantation of the dorsal lip of the newt gastrula, are arguably the most influential in the history of developmental biology. Hilde Mangold was a PhD student. She died in a house fire at age 26. Hans Spemann was awarded the Nobel Prize in 1935. He always referred to the work in his later publications as Hilde Mangolds experiment. Developmental Biology In a famous experiment in 1924, Mangold and Spemann transplanted a piece of the dorsal lip of a newt gastrula to the ventral side of a second gastrula. What happened to the second gastrula? A. the two lips inhibited each other and the embryo died B. the original lip formed a mouth, the new one did not C. both lips turned into mouths D. the original lip became an anus instead of a mouth E. the embryo formed a second, partial embryo on the ventral side In a famous experiment in 1924, Mangold and Spemann transplanted a piece of the dorsal lip of a newt gastrula to the ventral side of a second...
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This note was uploaded on 03/13/2010 for the course BIOG 1102 taught by Professor Robertturgeo during the Spring '10 term at Cornell University (Engineering School).
- Spring '10