01 first - PB HLTH C240D/STAT C245D and STAT 246 Course...

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Unformatted text preview: PB HLTH C240D/STAT C245D and STAT 246 Course Overview Practical Matters Other Courses PB HLTH C240D/STAT C245D Biostatistical Methods: Applications of Statistics to Genetics and Molecular Biology Sandrine Dudoit Division of Biostatistics and Department of Statistics University of California, Berkeley www.stat.berkeley.edu/~sandrine Spring 2009 Version: 16/01/2009, 21:37 PB HLTH C240D/STAT C245D and STAT 246 Course Overview Practical Matters Other Courses STAT 246 Statistical Genetics Haiyan Huang Department of Statistics and Division of Biostatistics University of California, Berkeley www.stat.berkeley.edu/~hhuang Spring 2009 PB HLTH C240D/STAT C245D and STAT 246 Course Overview Practical Matters Other Courses Outline 1 Course Overview 2 Practical Matters 3 Other Courses PB HLTH C240D/STAT C245D and STAT 246 Course Overview Practical Matters Other Courses Course Overview This course concerns statistical and computational methods for addressing inference problems that arise in genomic research . A common thread among these problems is their high-dimensional and computer-intensive nature. The course also concerns statistical computing resources, with emphasis on the R language and environment ( www.r-project.org ). PB HLTH C240D/STAT C245D and STAT 246 Course Overview Practical Matters Other Courses Course Overview Biological topics , to be discussed in terms of both statistical methodology and software implementation . Primer on genome biology. [SD; 4 lectures] I Part I: Cells, chromosomes, and cell division; DNA structure and replication; Proteins; Central dogma: transcription and translation; Pathways. I Part II: A historical perspective; Examples of genetic diseases. I Part III: Basic lab techniques; Overview of: genetic mapping, biological sequence analysis, high-throughput gene expression assays (microarrays and sequencing), biological annotation metadata analysis. Statistical analysis of meiosis. [SD; 4 lectures] I Mitosis and meiosis. I Crossover and recombination. I Genetic mapping. PB HLTH C240D/STAT C245D and STAT 246 Course Overview Practical Matters Other Courses Course Overview I Stochastic modeling of meiosis: No-chromatid-interference model; No-interference model; Crossover interference...
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This note was uploaded on 03/14/2010 for the course C 240D, C24 taught by Professor S.dudoit during the Spring '09 term at University of California, Berkeley.

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01 first - PB HLTH C240D/STAT C245D and STAT 246 Course...

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