BCH4024 - Allen Lecture 18 - 20

BCH4024 - Allen Lecture 18 - 20 - BCH 4024 (2010)...

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Unformatted text preview: BCH 4024 (2010) Recommended Readings From Lehninger Principles of Biochemistry for Allens Lectures In Metabolism Date Lecture 5 th Edition 2/5 Introduction to 485-488, 495-501 Intermediary Metabolism 2/8 Glycolysis I 527-551 2/9 Glycolysis II 583-589 2/10 Glycogen Metabolism 594-609 2/12 Gluconeogenesis I 551-558 2/15 Gluconeogenesis II 582-590 2/16 Tricarboxylic Acid Cycle I 615-638 2/17 Tricarboxylic Acid Cycle II 615-638 2/19 Tricarboxylic Acid Cycle III 615-638 2/22 Electron Transport/Oxidative 707-722,512-521 Phosphorylation I 2/23 Electron Transport/Oxidative 723-736 Phosphorylation II 2/24 Pentose Shunt 558-563 2/26 Lipid Structure and Function 343-357 3/1 Lipid Function 343-457 3/2 Fatty Acid Oxidation 647-665 3/3 Fatty Acid Biosynthesis 805-815,665-668 and Ketogenesis 3/5 Phospholipid Biosynthesis 820-827 3/15 Sterol Metabolism 831-845 3/16 Lipoproteins 831-845 BCH 4024 (2009) Recommended Readings From Lehninger Principles of Biochemistry Editions 4 and 5 for Allens Lectures In Metabolism Date Lecture 4 th Edition 5 th Edition 2/6 Introduction to 481-488 485-488, 495-501 Intermediary Metabolism 2/9 Glycolysis I 521-543 527-551 2/10 Glycolysis II 578-580 583-589 2/11 Glycogen Metabolism 560-570, 583-591 594-609 2/13 Gluconeogenesis I 543-549 551-558 2/16 Gluconeogenesis II 580-583 582-590 2/17 Tricarboxylic Acid Cycle I 601-623 615-638 2/18 Tricarboxylic Acid Cycle II 601-623 615-638 2/20 Tricarboxylic Acid Cycle III 601-623 615-638 2/23 Electron Transport/Oxidative 690-704,507-517 707-722,512-521 Phosphorylation I 2/24 Electron Transport/Oxidative 704-719 723-736 Phosphorylation II 2/25 Pentose Shunt 549-555 558-563 2/27 Lipid Structure and Function 343-357 343-357 3/2 Lipid Function 343-357 343-457 3/3 Fatty Acid Oxidation 631-650 647-665 3/4 Fatty Acid Biosynthesis 787-797, 650-652 805-815,665-668 and Ketogenesis 3/6 Phospholipid Biosynthesis 808-812 820-827 3/16 Sterol Metabolism 816-827 831-845 3/17 Lipoproteins 816-827 831-845 Intermediary Metabolism All Reactions Concerned With Storing and Generating Metabolic Energy Using That Energy in Cellular Processes Protein Polysaccharides Lipids Amino Acids Glucose and other sugars Glycerol and fatty acids Pyruvate Acetyl CoA NH 3 Electron Transport ATP CO 2 H 2 O Citric Acid Cycle Catabolism Yields ATP Protein Polysaccharides Lipids Amino Acids Glucose and other sugars Glycerol and fatty acids Pyruvate NH 3 Citric Acid Cycle Phosphoenol pyruvate Acetyl CoA Anabolism Uses ATP Regulation 1) Amount of Enzymes- compartmentalization- hormonal control- tissue specialization 2) Catalytic Activity of Enzymes- allosteric effectors- inhibitors- covalent modification 3) Accessibility of Substrates- compartmentalization- energy state ( i.e. ratios of ATP/ADP, NADH/NAD + ) Catabolism Reduced Substrate Oxidized Substrate O 2 H 2 O NAD + NADH Reduced Substrate Oxidized Substrate NADP + NADPH ATP ADP +Pi Electron transport Anabolism Small Oxidized Molecules Large Reduced Molecules NADPH NADP + ATP ADP + P i p 483 Lehn (487) 2. 2....
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BCH4024 - Allen Lecture 18 - 20 - BCH 4024 (2010)...

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