probset_6_2009

probset_6_2009 - Identify (a) all the loops and stems by...

Info iconThis preview shows pages 1–3. Sign up to view the full content.

View Full Document Right Arrow Icon
Problem Set 6 BMB 100A Fall, 2009 Name__________________ 1. What are the codons for Trp, Glu, Ile, Leu and Ser? 2. What is the minimum number of tRNAs required to recognize all of the codons for each amino acid in problem 1? What are their corresponding anticodon sequences? 3. How many codons can be deduced using the repeating block copolymer (AGCU)n as mRNA? What are they, and which amino acids do they code for? 4. Reconstruct in a standard chemical structure drawing the structures of the bases, sugars and phosphates, and their molecular interactions depicted in the electron density contour map (i) in your tRNA handout.
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
5. Draw a rough schematic of the 3-dimensional structure of tRNA, starting with the "cloverleaf" secondary structure model, and then folding it into the 3-d tertiary structure.
Background image of page 2
Background image of page 3
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: Identify (a) all the loops and stems by name, (b) the 5' and3' ends, (c) the two longest conserved sequences, (d) the seven crucial tertiary base-base interactions, (e) the anticodon (f) the point of attachment of the amino acid and (g) a turn. 6. Referring to the tRNA structure on your tRNA handout or in RASMOL, determine which pairs of nucleotides are closer to each other: (a) 5 and 8 vs. 7 and 49 (b) 10 and 14 vs. 15 and 59 (c) 10 and 56 vs. 19 and 57 (d) 5 and 67 vs. 22 and 53 (e) 9 and 46 vs. 10 and 47 7. Which bases in tRNA are not stacked? For each of them, can you explain why? 8. Peptide bond formation is one step in protein synthesis that does not require ATP or GTP. Explain where the energy of peptide bond formation comes from....
View Full Document

This note was uploaded on 03/16/2010 for the course BIOC 100A taught by Professor Harrynoller during the Winter '10 term at UCSC.

Page1 / 3

probset_6_2009 - Identify (a) all the loops and stems by...

This preview shows document pages 1 - 3. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online