ProblemSet6

ProblemSet6 - Bioc100B Winter 2010 Rubin Problem Set #6 Due...

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Bioc100B Winter 2010 Rubin Problem Set #6 Due Tuesday, March 9th 10:00 A.M. 1) Choosing from palmitic, oleic, and linoleic acid as fatty acids, draw the structure of a phosphatidylserine, triglycerol, and a sphingolipid. Name your compounds using common fatty acid names. Of all the structures you could have potentially drawn, identify and name the compounds with the lowest and highest melting points. 2) What is the minimum number of residues an α helix must have to span the hydrophobic portion of a phospholipid bilayer? What is the minimum number of residues a β strand must have if it is inserted at a 45-degree angle to the bilayer plane? Why are most secondary structure elements in proteins longer than this minimum amount? 3) In lecture, f luorescence r ecovery a fter p hotobleaching (FRAP) was described as a method for measuring lateral diffusion rates of lipids in membranes. Briefly describe an experiment in which you use FRAP to a) measure the melting temperature of a membrane b) measure catalytic activity of a flipase
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ProblemSet6 - Bioc100B Winter 2010 Rubin Problem Set #6 Due...

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