Unformatted text preview: molecules of glucose to be transported into the cell? Assume the diameter of a red blood cell is 8 µm, and the concentration gradient ([A] out – [A] in ) remains constant at 1 μ M. 5) Sketch a plot of J glucose as a function of [glucose] in the presence of the GLUT1 glucose transporter. Sketch a new plot and describe how the plot has changed in the following circumstances a) doubling the [GLUT1] concentration b) addition of a molecule that interacts with the glucose-binding site c) addition of a molecule that prevents the T1 T2 conformational change 6) Explain why it is critical that the lactose permease only interconvert between the E1 and E2 conformations when either both or neither of the ligands are bound. What is the similar safeguard mechanism in the Na-K ATPase?...
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- Winter '10
- Glucose, Receptor antagonist, Voet