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Unformatted text preview: O O O O OH OMe O HO NMe 2 N Me erythromycin A Zithromax TM Shown above are structures of two antibiotics, erythromycin A, and Zithromax. Because erythromycin A breaks down in the acidic environment of the stomach, patients on erythromycin must take 1000 mg a day for 14 days; Zithromax is stable in the stomach, and thus patients need only take 300 mg a day for 7 days. Looking at the two structures, and remembering what you know about the reactivity of ketones, please draw the structure of the erythromycin A breakdown product. Why doesnt Zithromax breakdown in an analogous fashion?...
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- Spring '08