CE555 - Chapter 1- Lecture Notes [Compatibility Mode]

CE555 - Chapter 1- Lecture Notes [Compatibility Mode] -...

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1 Chapter 1: Microorganisms and Microbiology Part I: Introduction to Microbiology Part II: Pathways of Discovery in Microbiology The Basis of Life • Math-> Physics-> Chemistry-> Biology – All life is based on oxidation and reduction reactions – Reactions either release or use energy Energy coin of life is ATP – Energy coin of life is ATP
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2 Part I: Introduction to Microbiology Two main things I want you to understand: (1) Basic science of understanding life. Elucidate the genetic and biochemical basis of unicellular and multicellular life. Amenable to biochemical and genetic study. (2) Applications of microbiology to human needs . Causative agents of some important human, animal, and plant diseases . Industrial products, including antibiotics, energy, food . Affects the quality of human life . Importance of microorganisms: Essential role to maintain and support life on planet via biogeochemical cycling of key elements. If not for bacteria, we would not be here.
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3 The cell: fundamental unit of life Dynamic entity (not a closed system) that forms the fundamental unit of life. Contains a variety of chemicals and subcellular structures Contains a variety of chemicals and subcellular structures. Highly organized structure. Made primarily from a few choice atoms (C,N, P, O, H). Contains 4 chemical components( macromolecules) : Proteins nucleic acids lipids polysaccharides Proteins, nucleic acids, lipids, polysaccharides . Chemistry and arrangement of macromolecules make cells differ form one another. Key structures: Cytoplasmic membrane - Barrier that separates the inside of the cell from the outside. Cytoplasm – where “machinery” (chemicals/structures) for cell growth and function are present. Nucleus/nucleoid – store DNA (genetic info) and ribosomes (structures upon which proteins are made).
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4 Characteristics of living cells: Cells as Machines and Coding Devices Machines Chemical transformations with the catalyst of enzymes – proteins capable of accelerating the rate of chemical reactions. Coding devices Store and process genetic information that is Store and process genetic information that is passed on to offspring during reproduction.
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5 Cells as Machines and Coding Devices (cont’d) Union of cellular attributes is growth.
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CE555 - Chapter 1- Lecture Notes [Compatibility Mode] -...

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