PS09-Sol - Genetics 320, Problem Set 9 (10 points) Due Wes....

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Genetics 320, Problem Set 9 (10 points) Due Wes. 23 Nov 2005 at 11 am 1 (2 points) : Consider a cross between an M 2 M 3 father and a M 2 M 4 mother. In the offspring, the marker genotype is scored, along with nose length and the following data are observed. Genotype Mean nose lenght M 2 M 2 100 M 2 M 3 100 M 2 M 4 300 M 3 M 4 300 (a) Is there evidence that the marker is linked to a segregating QTL for nose length in the father? M 2 - M 3 = (100 + 300) / 2 - (100 + 300) / 2=0 . No evidence (b) Is there evidence that the marker is linked to a segregating QTL for nose length in the mother? M 2 - M 4 = (100+100) / 2 - (300+300) / 2= - 200 . Evidence that the mother is heterozygous for a QTL linked to the marker. Given this result, father is homozygous at this QTL. 2 (2 points) : Consider a locus with four alleles ( A 1 to A 4 ) at the following frequencies: p 1 =0 . 1 , p 2 =0 . 2 , p 3 =0 . 3 , p 4 =0 . 4 . Assume random mating and all other Hardy-Weinberg conditions. What is the frequency of (a) A 2 A 3 ? 2 p 2 p 3 =0 . 12 (b) A 4 A 4 ? p 2 4 =0 . 16 (c) All heterozygotes involving allele A 2
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This homework help was uploaded on 04/03/2008 for the course BIO 320 taught by Professor Walsh,weinert during the Fall '07 term at University of Arizona- Tucson.

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PS09-Sol - Genetics 320, Problem Set 9 (10 points) Due Wes....

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