2004 - BOTANY/ZOOLOGY: Date: 14 May, 2004 UNIVERSITY OF...

Info iconThis preview shows pages 1–3. Sign up to view the full content.

View Full Document Right Arrow Icon
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 2
Background image of page 3
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: BOTANY/ZOOLOGY: Date: 14 May, 2004 UNIVERSITY OF HONG KONG BACHELOR OF SCIENCE: FINAL EXAMINATION BIOL1106 Genetics Time: 6 :30pm-8:30pm Candidates may use any self-contained, silent, battery-operated and pocket-sized calculator. The calculator should have numeral-display facilities only and should be used only for the purpose of calculation. It is the candidate's responsibility to ensure that his/her calculator operates satisfactorily. Candidates must record the name and type of their calculators on the front page of their examination scripts. Answer any FIVE questions. All questions carry equal marks. 1. In Jimsonweed, purple flower (P) is dominant to white (p), and spiny pods (S) are dominant to smooth (s). In a cross between a Jimsonweed homozygous for white flowers and spiny pods and one homozygous for purple flowers and smooth pods, determine the phenotype of (a) The F1; (b) The F2; (c) The progeny of a cross of the F1 back to the purple, smooth parent. A dominant gene in corn (Kn) results in the proliferation of vascular tissues in a trait called "knotted leaf“. A heterozygous knotted leaf plant is crossed to a normal plant producing 153 knotted leaf and 178 normal progeny. (a) Propose a hypothesis to explain the results. (b) Test your hypothesis using the Chi-square method. (c) Apply Yates' correction term in the calculation of Chi-square. Are these results consistent with the hypothesis? Since Mendel’s time the definition of “gene” has been revised many times. Describe each of these revisions briefly. Discuss these definitions based on current knowledge. Describe the distinctive morphological features of metaphase chromosomes. (a) Describe the unique features of the DNA molecule. (b) Describe genome sequencing. 6. A total of 782 pregnant female mice were caught from a large population in the wild. Molecular genotyping was conducted for each mother and one of her randomly chosen offspring. At an enzyme locus, the following results were obtained: Offspring genotype Maternal genotype AIAI A1A2 A2A2 AA] 41 70 —~ AA; 65 173 119 A2A2 — 127 187 (a) Find the allele frequency of A1 among males that fertilized A1A1 females. (b) Find the allele frequency of A1 among males that fertilized A2A2 females. (0) Find the allele frequency of A1 among all females. (d) Find the allele frequency of A1 among the offspring across all female genotypes. (e) Do the two estimates 0 f allele frequency 0 f A1 differ b etween (c) and (d)? If the answer is yes, give the possible causes for the observed difference. 7. Three genotypes are present at the locus determining the MN blood groups in a human population, which is in Hardy-Weinberg equilibrium at this locus: MM MN NN (a) If there are 10 times as many MN as NN genotypes in the population, what is the frequency of the N allele? (b) If 42% of the individuals in the population are MN, and M is more common than N, what is the frequency of the M allele? (0) There are two ways to calculate the frequencies of M and N alleles: by taking the square root of the frequency of each type of homozygotes, or by counting alleles for the observed genotypes. Which method do you prefer? And why? The probabilifles of exceeding dlfierenf chi-square values for degree: of freedom from 1 to 50 when {he ‘ expected hypothesis is true' W \OOOVQMAWNNS‘ \~\\~N MQWNKQ 20 25 30 50 Prohabfllfies WM .95 .004 .10 .35 71 1.64 2.17 2.73 3.33 3.94 4.58 5.23 5.89 6.57 7.26 10.85 14.61 111.49 34.76 1.15' .90 .016 .21 .58 1.06 1 .6 1 2.20 2.83 3.49 4. 17 4.87 5.58 6.30 7.04 7. 79 8.55 12.44 16.47 20.60 37.69 .70 I .15 .71 1.42 2.20 3.00 3.83 4.67 5.53 6.39 7.27 8.15 9.03 9.93 10.82 1 1.72 16.27 20.87 25.51 44.3 1 .50 .46 1.39 2.37 3.36 4.35 5.35 6.35 7.34 8.34 9.34 10.34 1 1.34 12.34 13.34 14.34 19.34 24.34 29.34 49.34 .30 1.07 2.41 3.67 4.88 6.06 7.23 8.38 9.52 10.66 1 1.78 12.90 14.01 15. 12 16.22 17.32 22.78 28.17 33.53 54.72 .20 1.64 3.22 4.64 5.99 7.29 8.56 9.80 11.03 12.24 13.44 14.63 15.81 16.99 18.15 19.31 25.04 30.68 36.25 58.16 .10 2.71 4.61 6.25 7.78 9.24 10.65 12.02 13.36 v 14.68 15.99 17.28 18.55 19.81 21.06 22.31 28.41 34.38 40.26 63.17 .05 ‘ 3.84 5.99 7.82 9.49 1 1.07 12.59 14.07 15.5 1 16.92 18.31 19.68 2 1.03 22.36 23 .69 25.00 31.41 37.65 43.77 67.51 . 01 6.64 9.21 1 1.35 13.28 15.09 16.81 18.48 20.09 21.67 23.21 24.73 26.22 27.69 29.14 30.58 37.57 44.31 50.89 76.15 (10 not reject ’ rcjecl a1 .05 1evc1 .001 10.83 13.82 16.27 18.47 20.52 22.46 24.32 26.13 27.88 29.59 3 1.26 32.91 34.53 36.12 37.70 45.32 52.62 59.70 86.66 ' Abridged 5mm Tabl. W of Fish" and Yam, of 11w authon and publishers. END OF PAPER Stofixficnl Tabha for Biological, Agriculluml and Modt’ool Rewaldu, Oliver and Soyd Ltd.. Edinburgh, by permission ...
View Full Document

Page1 / 3

2004 - BOTANY/ZOOLOGY: Date: 14 May, 2004 UNIVERSITY OF...

This preview shows document pages 1 - 3. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online