ASM 345 Study Guide 1

ASM 345 Study Guide 1 - understand how parasites develop...

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ASM345: Disease and Human Evolution Study guide #1: General Concepts/Debates you should understand: What is disease and what causes it? How does your body try to defend against disease agents? What diseases were likely common among early humans? How do prions work and what appears to make someone susceptible? What is the first epidemiological transition in humans? How has agriculture affected patterns of disease? What factors influence the spread of a disease? What is the relationship between parasite transmission and virulence? What is meant by the "arms race" and "red queen" theories for parasite/host evolution? What are advantages/disadvantages for being a "generalist" or "specialist" for parasites? Why/How does malaria affect young vs. older adults? How will studying genes and genomes and natural disease resistance in humans help us
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Unformatted text preview: understand how parasites develop drug resistance? What criteria/information is explicitly important in the diagnosis of a disease? How can we determine where/when/how a disease has historically impacted human populations? Terms to know: evolution disease commensalism mutualism parasitism worms fungi protozoa bacteria viruses prions natural selection negative (or purifying) selection directional selection balancing selection selection crowd disease domestication epidemic pandemic sickle-cell anemia G6PD deficiency hemoglobin lesion acute vs. chronic disease symptoms anemia host resistance pathogenicity host/vector host switch symptomatic asymptomatic prodrome Plasmodium Anopheles clastic lesion blastic lesion transmission virulence epidemiology...
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