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lecture_4 - SOLID LIQUID SEPARATION: CENTRIFUGATION CHARLES...

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SOLID LIQUID SEPAR A TION: CENTRIFUGATION CHARLES L. COONEY DOWNSTREAM PROCESSING COURSE MIT Professional Institute August 1-5, 2005 Figure by MIT OCW.
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Centrifugation is Effective in Volume Reduction Characteristics of process streams in primary recovery •Volume at or near process maximum •Heterogeneous solid/liquid mixture •Particle size distribution •Typical particle sizes: •Bacteria 1 to 2 µ •Yeast 3 to 5 µ •Actinomyces 2 to 30 µ •Molds 4 to >30 µ •Microbial flocs 10 to >100 µ •Cell debris <1 µ •Solids content: 1-10% dry basis 5-50% wet basis •Time variable product and stream quality •Viscosity: 1 to >5,000 cp •Temperature: 4-40 C •Mechanically (shear) sensitive materials •Temperature and pH sensitive materials •Potentially toxic materials
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Centrifuge Equipment Process Needs •Cleaning in place (CIP) •Steam in place (SIP) •Automation for start-up and operation •Short process times •Flexibility in process stream properties •Temperature control •Containment to prevent entry of contaminants and release of solvents or toxic materials •Corrosion resistance
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This note was uploaded on 03/24/2010 for the course ARCH 456 taught by Professor Arch during the Spring '10 term at MIT.

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lecture_4 - SOLID LIQUID SEPARATION: CENTRIFUGATION CHARLES...

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